Abstract The amazing diversity of B cells within the tumor microenvironment is the basis for the diverse development of B cell-based immunotherapies.Here, we focus on elucidating the mechanisms of tumor intervention mediated by hiboost 4k smart link four tumor-infiltrating B lymphocytes.Naive B cells present the initial antigen, germinal center B cell subsets enhance antibody affinity, ps5 price new jersey and immunoglobulin subtypes exert multiple immune effects, while regulatory B cells establish immune tolerance.Together they reflect the complexity of the changing dynamics of cancer immunity.Additionally, we have investigated the dynamic effects of tumor-infiltrating B lymphocytes in immunotherapy and their relationship to prognosis, providing new insights into potential treatment strategies for patients.